Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(PDT) With Chlorin-e6 in Treating Moderate to Severe Acne

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-50
SponsorXiyuan Hospital of China Academy of Chinese Medical Sciences

About this trial

This study aims to evaluate the clinical efficacy, safety and tolerability of a photodynamic therapy(PDT) based on a new photosensitizer, Chlorin-e6, in the treatment of moderate to severe acne. The hypothesis is that the therapy has good efficacy, safety and tolerability.

Eligibility criteria

Qualifiers

Subject is male or non-pregnant female 18 years of age and younger than 50 years of age.

Subject has moderate to severe facial acne vulgaris.

Subject has provided written informed consent.

Disqualifiers

People who are taking photosensitive drugs;

Allergic to any component of the photosensitizer;

porphyrins or allergies to porphyrins, with a history of photosensitivity;

Pregnant or lactating women and those planning to become pregnant within 3 months;

Trial design

Treatments tested in this trial

  • N-chlorin e6 triglumine
  • acne removal surgery

Treatment groups

46 Participants
are divided into 2 treatment groups