Sugammadex Dose Finding Under Two Years Old
ConditionNeuromuscular Blockade
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
AgeUp to 23
SponsorSang-Hwan Ji
About this trial
This is a prospective dose-finding study of sugammadex for conventional reversal of rocuronium-induced neuromuscular blockade in children under two years of age. This study will explore 50% effective dose and 95% effective dose of sugammadex for reversal of neuromuscular blockade in less than two minutes under biased coin up-and-down method.
Eligibility criteria
Qualifiers
Childern younger than 2 years old who are scheduled to undergo surgery under general anesthesia
American Society of Anesthesiologists Physical Status 1 or 2
Disqualifiers
History of hypersensitivity to rocuronium or any anesthetics
Presence of cardiovascular or genitourinary disease
Presence of severe renal dysfunction or in need of dialysis
Presence of severe hepatic dysfunction or coagualtion disorder
Trial design
Treatments tested in this trial
- Sugammadex
Treatment groups
33 Participants
are divided into 1 treatment groupSponsors and collaborators
Sang-Hwan Ji
Lead sponsor
Seoul National University Hospital
Sponsor institution
Source ClinicalTrials.gov