Systemic Treatment Options for Generalized Lichen Planus

ConditionLichen Planus
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-60
SponsorSheikh Zayed Medical College

About this trial

Lichen planus is a chronic inflammatory skin condition with unknown etiology. It requires a long term treatment. Evaulating the most efficacious, safe and affordable treatment option is the need of the hour. This study is going to compare the efficacy of two familiar drugs (acitretin and methotrexate) in the treatment of generalized lichen planus as to find out the relatively more effective and safer treatment.

Eligibility criteria

Qualifiers

Age: 18-60 years

Gender: both male and female

Type of Lichen planus: generalized lichen planus

Patients not taking prior treatment in last 1 month

Disqualifiers

Pregnancy and lactating females

Bleeding disorders

Abnormal liver function tests

Platelet count less than 100000

Trial design

Treatments tested in this trial

  • Methotrexate (drug)
  • Acitretin

Treatment groups

124 Participants
are divided into 2 treatment groups

Sponsors and collaborators