About this trial
The aim of this clinical trial is to evaluate the efficacy of tesamorelin as a therapy for peripheral nerve injuries. The investigators hypothesize that treatment with tesamorelin will result in faster and more substantial recovery of motor and sensory function following surgical repair of injured peripheral nerves. Patients with upper extremity nerve injuries will be randomly assigned to receive either tesamorelin treatment or no treatment. Assessments for nerve regeneration, muscle function, and sensation will be conducted every three months for a total of 12 months. Outcomes in patients receiving tesamorelin will be compared to those in the untreated group to determine the effectiveness of tesamorelin as a therapeutic intervention for nerve injuries.
Eligibility criteria
Qualifiers
Ulnar nerve laceration at the wrist, repaired primarily
Disqualifiers
Certain cancers (active or in the past)
Uncontrolled diabetes or hypertension
Certain pituitary problems
Oral contraceptives
Trial design
Treatments tested in this trial
- Tesamorelin 2 Milligrams (MG)
Treatment groups
Sponsors and collaborators
Johns Hopkins University
Lead sponsor
United States Department of Defense
Collaborator