The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18-50
SponsorBritish University In Egypt
About this trial
The goal of this randomized clinical trial is to evaluate the capability of the material to exert bacterial reduction of diclofenac sodium versus of that calcium hydroxide paste when these materials are used as intracanal medications in permanent molar teeth with chronic apical periodontitis.
The main question\[s\] it aims to answer are:
• Will the diclofenac sodium (NSAIDs) possess antimicrobial efficacy to be used effectively as an intracanal medicament similar to that of calcium hydroxide in primary endodontic treatment? Participants will be allocated randomly into three equal groups by using computer generated randomization, according to the type of intracanal medication.
Eligibility criteria
Qualifiers
Patients with teeth diagnosed with apical periodontitis
Periapical Index (PAI) ≥ 2
The teeth are restorable
Disqualifiers
Teeth with immature roots
Non restorable teeth
Medically compromised patients with systemic complication that would alter the treatment.
Teeth with internal/external root resorption
Trial design
Treatments tested in this trial
- Diclofenac Sodium
- Calcium hydroxide
Treatment groups
48 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov