The study aims to explore the efficacy and safety of an intravaginal acetic acid thermoreversible gel in Chinese women of reproductive age, comparing it with nonoxinol gel by assessing the six-month Pearl Index and the incidence of any side effects.
1) Aged between 20 and 45 years old;
2) Regular menstrual cycles (cycle length 25-35 days, menstruation lasting up to 7 days);
3) Have a history of pregnancy with the current partner at least once;
4) Currently engaging in regular sexual activity and planning to do so in the next six months (at least once a week);
1) Amenorrhoea for more than 1 month, suspected pregnancy;
2) Moderate to severe erosive changes in the cervix;
3) Vaginal cleanliness grade III or above;
4) Trichomonas, fungal vaginitis, and bacterial vaginosis, among other conditions, have not been cured;
National Research Institute for Family Planning, China
Lead sponsor
Shanghai Jinxiang Latex Products Co.
Collaborator