The Effect of Probiotics on Gut Microbiota Changes in Healthy Chinese Adults During Short-Term European Travel: A Randomised, Double-Blind, Placebo-Controlled Clinical Trial

ConditionHealthy Adult
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorMin-Tze LIONG

About this trial

This study aims to evaluate the efficacy of a probiotic complex (containing Bifidobacterium animalis subsp. lactis B94 and Lacticaseibacillus helveticus R0052) in maintaining gut microbiota homeostasis and supporting physiological and psychological stability among healthy Chinese adults during short-term travel to Europe.

Eligibility criteria

Qualifiers

Aged 18-65 years, regardless of gender;

Planning to undertake a short-term round-trip journey to Europe (within 7 days);

Able to understand and willing to comply with the study protocol, and to cooperate with study procedures;

Voluntarily sign the informed consent form before any study-related procedures are initiated.

Disqualifiers

Diseases that may affect the evaluation of trial results, such as immune dysfunction, severe renal/hepatic dysfunction, severe cardiovascular disease, malignant tumors, acute or chronic infections, etc.;

Use of probiotic preparations, antibiotics, hormones, immunosuppressants, biological agents, or JAK inhibitors within 4 weeks;

Subjects with diagnosed or uncontrolled parasitic infections;

Patients receiving long-term medication for chronic diseases;

Trial design

Treatments tested in this trial

  • Placebo
  • Probiotic

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Min-Tze LIONG

Lead sponsor

Universiti Sains Malaysia

Sponsor institution

Tsinghua University

Collaborator