Tislelizumab Combined With Capecitabine for Nasopharyngeal Carcinoma With Residual EBV DNA After Radiotherapy

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorFudan University

About this trial

This study aims to explore the efficacy and safety of tislelizumab combined with capecitabine in nasopharyngeal carcinoma patients with residual plasma EBV DNA after radiotherapy.

Eligibility criteria

Qualifiers

Age ≥18 years;

Histologically confirmed nasopharyngeal carcinoma;

Expected survival time ≥12 weeks;

ECOG performance status: 0-1;

Disqualifiers

Histologically confirmed keratinizing squamous cell carcinoma (WHO I);

Distant metastasis detected by pre-treatment clinical or imaging examinations;

History of allergy to any component of monoclonal antibodies, tislelizumab, or capecitabine;

Autoimmune-related hypothyroidism on stable thyroid hormone replacement therapy;

Trial design

Treatments tested in this trial

  • Adjuvant therapy

Treatment groups

76 Participants
are divided into 2 treatment groups

Sponsors and collaborators