To Evaluate the Efficacy and Safety of JPI-547 in Combination With Bevacizumab as Maintenance Therapy in Relapsed Ovarian Cancer

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexFemale
Age19+
SponsorOnconic Therapeutics Inc.

About this trial

This study aims to to evaluate the efficacy, safety, and pharmacokinetics of JPI- 547 with bevacizumab maintenance therapy in relapsed ovarian cancer patients

Eligibility criteria

Qualifiers

Histologically or cytologically confirmed recurrent ovarian cancer, fallopian tube cancer, or primary peritoneal cancer [High-grade serous carcinoma (HGSC), Grade 2/3 endometrioid carcinoma]

Patients whose BRCA 1/2 gene mutation status and/or Homologous Recombination Deficiency (HRD) status.

Patients who received platinum-based chemotherapy followed by PARP inhibitor maintenance therapy,

Patients who had received chemotherapy before participating in the clinical trial and responded to platinum-based chemotherapy.

Disqualifiers

Patients with a history of severe drug hypersensitivity or hypersensitivity to the investigational drug, its components, or drugs within the same class.

Individuals with dysphagia

Patients with a confirmed specific medical history or a past surgical history.

Patients with specific comorbidities or medical abnormalities.

Trial design

Treatments tested in this trial

  • JPI-547
  • Bevacizumab

Treatment groups

81 Participants
are divided into 2 treatment groups

Sponsors and collaborators