Topical GHK-Cu Gel for Acute Skin Wound Healing
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-55
SponsorHudson Biotech
About this trial
This study will evaluate whether a topical gel containing GHK-Cu (a copper(II)-peptide complex) can safely speed up healing of small, standardized skin wounds in healthy adults compared with a matching vehicle gel.
Participants will receive two small punch-biopsy wounds on the upper arm; each wound will be randomly assigned to receive GHK-Cu gel or vehicle gel under identical dressings. Wounds will be photographed and assessed over 3 weeks, with a follow-up visit to evaluate scar quality.
Eligibility criteria
Qualifiers
Age 18 to 55 years at screening.
Healthy adult as determined by medical history and limited physical examination.
Body mass index (BMI) 18.0 to 30.0 kg/m².
Willing and able to comply with study visits and daily product application for 14 days.
Disqualifiers
Known allergy or sensitivity to copper, peptides, gel excipients, adhesives, or dressings used in the study.
History of abnormal wound healing, hypertrophic scarring, or keloid formation.
Clinically significant dermatologic disease near the intended wound site (e.g., eczema, psoriasis, active infection).
Diabetes mellitus, peripheral vascular disease, immunodeficiency, or other condition that may impair wound healing (investigator judgment).
Trial design
Treatments tested in this trial
- GHK-Cu Gel (Copper(II)-peptide complex)
- vehicle Gel (placebo comparator)
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov