Toripalimab Combined With Radiotherapy in the Treatment of Oligometastatic Nasopharyngeal Carcinoma

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorXinqiao Hospital of Chongqing

About this trial

The aim of the study was to determine the efficacy and safety of toripalimab combined with radiotherapy in the treatment of oligometastatic nasopharyngeal carcinoma

Eligibility criteria

Qualifiers

Must have signed written informed consent and able to comply with study procedure

18-75 years old

Histologically or cytologically confirmed nasopharyngeal carcinoma

Pathology or imaging confirmed metastatic nasopharyngeal carcinoma.( Clinical stage of IVB according to the 8th edition of AJCC)

Disqualifiers

Allergy to any component of toripalimab

With any active autoimmune disease or a history of autoimmune disease that may relapse

Any active malignancy ≤ 2 years before randomization except for the specific cancer under investigation in this study and any locally relapsed cancer that has been cured after treatment (eg, resected basal or squamous cell skin cancer, superficial bladder cancer, carcinoma in situ of the cervix or breast)

Received corticosteroid therapy at a dose ≥ 10 mg prednisone per day or any other systemic immunosuppressive therapy within 14 days prior to enrollment.

Trial design

Treatments tested in this trial

  • Toripalimab

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators

Xinqiao Hospital of Chongqing

Lead sponsor

Southwest Hospital, China

Collaborator

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Collaborator

Chongqing University Cancer Hospital

Collaborator