About this trial
The aim of the study was to determine the efficacy and safety of toripalimab combined with radiotherapy in the treatment of oligometastatic nasopharyngeal carcinoma
Eligibility criteria
Qualifiers
Must have signed written informed consent and able to comply with study procedure
18-75 years old
Histologically or cytologically confirmed nasopharyngeal carcinoma
Pathology or imaging confirmed metastatic nasopharyngeal carcinoma.( Clinical stage of IVB according to the 8th edition of AJCC)
Disqualifiers
Allergy to any component of toripalimab
With any active autoimmune disease or a history of autoimmune disease that may relapse
Any active malignancy ≤ 2 years before randomization except for the specific cancer under investigation in this study and any locally relapsed cancer that has been cured after treatment (eg, resected basal or squamous cell skin cancer, superficial bladder cancer, carcinoma in situ of the cervix or breast)
Received corticosteroid therapy at a dose ≥ 10 mg prednisone per day or any other systemic immunosuppressive therapy within 14 days prior to enrollment.
Trial design
Treatments tested in this trial
- Toripalimab
Treatment groups
Sponsors and collaborators
Xinqiao Hospital of Chongqing
Lead sponsor
Southwest Hospital, China
Collaborator
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Collaborator
Chongqing University Cancer Hospital
Collaborator