Tranexamic Acid in Nasal Mohs Reconstruction
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorVanderbilt University Medical Center
About this trial
This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.
Eligibility criteria
Qualifiers
Adults at least 18 years of age undergoing local flap reconstruction (bilobe flap, note flap dorsal nasal flap, advancement flap) of a nasal defect following Mohs micrographic surgery. Reconstructive procedures will be performed by Drs. Yang or Patel in the division of Facial Plastic Surgery in the Department of Otolaryngology, Head and Neck Surgery at Vanderbilt University Medical Center.
No other facial plastic procedure or sinus surgery performed simultaneously.
Lack of all the below
Disqualifiers
Known allergy to TXA
Intracranial bleeding
Known defective color vision
History of venous or arterial thromboembolism
Trial design
Treatments tested in this trial
- Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine)
- Control (1% lidocaine with 1:100,000 epinephrine)
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov