Trial to Evaluate the Effects of Naltrexone in Nonsuicidal Self-injury
ConditionNonsuicidal Self-Injury
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age16+
SponsorSeoul National University Hospital
About this trial
The goal of this clinical trial is to learn if naltrexone works to treat nonsuicidal self-injurious behavior in adolescents and adults.
Eligibility criteria
Qualifiers
Age: 16 years of age or older
Clinical interviews meet DSM-5's nonsuicidal self-injury diagnostic criteria
Nonsuicidal self-injurious behavior has been observed more than once in the past two months
Obsessive Compulsive Drinking Scale general craving item 2 or more points (strong desire)
Disqualifiers
currently in psychotic or manic conditions
currently experiencing serious suicidal thoughts
history of substance-related disorders including opioid
do not agree to use very effective contraception from the time of signing the test subject's consent form to the end of study period (non-fertility women and postmenopausal women excluded from the contraception requirements)
Trial design
Treatments tested in this trial
- Naltrexone
- Placebo
Treatment groups
150 Participants
are divided into 2 treatment groupsSponsors and collaborators
Seoul National University Hospital
Lead sponsor
Whanin Pharmaceutical Company
Collaborator
Source ClinicalTrials.gov