Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorHebei Medical University Fourth Hospital

About this trial

This study is a single-center, single-arm, prospective clinical trial designed to evaluate the efficacy of local excision followed by postoperative chemoradiotherapy in patients with early-stage low/ultra-low rectal cancer. The study plans to enroll 60 patients with T1-2N0M0 low/ultra-low rectal cancer.

Eligibility criteria

Qualifiers

Age ≥18 years, regardless of gender

ECOG performance status 0-1

Biopsy-proven rectal adenocarcinoma

Distal margin of primary tumor ≤8 cm from anal verge

Disqualifiers

Failure to meet the above inclusion criteria

Patients refusing to sign informed consent

Impaired cognitive function or psychiatric disorders

Patients deemed ineligible by investigators

Trial design

Treatments tested in this trial

  • Local Tumor Resection
  • Radiotherapy
  • Chemotherapy

Treatment groups

60 Participants
are divided into 1 treatment group