Female patients undergoing surgical treatment for early breast cancer and meeting the inclusion criteria for adjuvant breast radiotherapy were randomized into two groups. One group will receive adjuvant whole-breast radiotherapy in ultra-hypofractionated regimen of 26 Gy in 5 fractions. In contrast, the other group will receive partial breast irradiation with a dose of 26Gy in 5 fractions.
The study's objective is to compare the effects of both breast radiotherapy protocols in terms of locoregional disease control and survival and to compare the adverse effects of radiotherapy between the two protocols. To determine if there is a correlation between different parameters and the efficacy and degree of toxicity for both protocols.
Breast-conserving surgery
Invasive ductal carcinoma
Age ≥ 50
Tumor size ≤ 3 cm
Neoadjuvant systemic therapy
TNBC (triple-negative breast cancer)
Extensive intraductal component (EIC)
Lymphovascular invasion (LVI)