About this trial
The aim of this study is to evaluate the use of a fixed dose of 3.66 mcg of follitropin delta (Rekovelle) on ovarian response during ovarian stimulation for intrauterine insemination (IUI). The assumption is that this fixed dose will be effective while minimizing the risk of multiple pregnancies. A recent study demonstrated the efficacy of follitropin delta for ovarian stimulation in IUI, and it has been approved in France for controlled ovarian stimulation in assisted reproductive techniques such as in vitro fertilization (IVF) and IVF with intracytoplasmic sperm injection (ICSI). With an adapted dose of Rekovelle for patients with regular menstrual cycles, ovarian stimulation is optimized from the first attempt, promoting the development of two follicles to improve pregnancy chances while reducing the risk of multiple pregnancies. This approach aims to achieve pregnancy faster and provide a more comfortable treatment experience.
Eligibility criteria
Qualifiers
Normo-ovulatory patients
18 - 38 included years old
BMI between 18 and 29 included kg/m²
Regular menstrual cycles
Disqualifiers
Endometriosis Stage III
Total mobile sperm count <1 million
Severe spermatogenesis disorders
Women with Poly Cystic Ovary Syndrom
Trial design
Treatments tested in this trial
- REKOVELLE (Follitropin Delta)
Treatment groups
Sponsors and collaborators
Centre Hospitalier Intercommunal Creteil
Lead sponsor
Ferring Pharmaceuticals
Collaborator