Uterine Transplant in Absolute Uterine Infertility (AUIF)
ConditionFemale Infertility
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexFemale
Age18-40
SponsorBrigham and Women's Hospital
About this trial
This study will examine the feasibility of initiating a uterine transplant program for Absolute Uterine Factor Infertility (AUFI) at Brigham and Women's Hospital. The investigators plan to screen 30 patients with a goal of enrolling 10 patients. (5 donors and 5 recipients) After careful screening, appropriate candidates will undergo IVF, Uterine Transplantation, Embryo Transfer, Pregnancy and Delivery. Once the uterus is explanted, five years of follow-up is planned.
Eligibility criteria
Qualifiers
None
Disqualifiers
Age 18-40
Clinical evidence of AUFI (Absolute Uterine Factor Infertility)
Able to produce at least 6 normal embryos by IVF for future use
Reasonable weight with BMI (Body Mass Index) less than 30.
Trial design
Treatments tested in this trial
- Uterine Transplant
Treatment groups
10 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov