WALNUTS for POWER: Polyphenols, Omega-3 Fatty Acids, Weight Loss, and EneRgy
ConditionProstate Cancer
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexMale
Age18+
SponsorStephen Freedland
About this trial
This is a randomized control trial testing the effect of walnut supplementation on prostate cancer progression in 50 men with biopsy confirmed prostate cancer and planning to undergo RP. Patients consented to the study will be randomly assigned to either continue their usual diets (control arm) or to the walnut arm for 4-10 weeks depending on the window between their consent date and the date for RP.
Eligibility criteria
Qualifiers
Pathologically confirmed prostate adenocarcinoma.
Diagnostic biopsy cores with ≥10 cores with each core examined separately to determine exact tumor location.
Biopsy grade group 2 or higher (Gleason ≥7).
Planning to undergo RP.
Disqualifiers
Allergy to nuts.
History of receiving hormone therapy or antiandrogen therapy.
Use of 5-alpha reductase inhibitors in the past 6 months.
Prior prostate radiotherapy (external beam or brachytherapy) or prior prostate cryotherapy.
Trial design
Treatments tested in this trial
- walnuts
- usual diet
- phone counseling with dietitian
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Stephen Freedland
Lead sponsor
Cedars-Sinai Medical Center
Sponsor institution
California Walnut Commission
Collaborator
Source ClinicalTrials.gov