About this trial
the goal of the study is to improve the quality of life of patients on antipsychotic medications and increase the rate of compliance to treatment.
Primary objective:
1.To determine the effectiveness of probiotics to decrease the weight gained as a result of antipsychotic medications.
Secondary objective:
1\. To determine the effect of probiotic supplementation on the psychological state of patients.
Eligibility criteria
Qualifiers
Adult schizophrenia patients (18-45 years) on second generation antipsychotics Stable patients with a total positive and negative syndrome scale (PANSS) score of ≤60.
Disqualifiers
Taking probiotics, fiber supplements, antibiotics and laxatives in the last 6 weeks.
Comorbid gastrointestinal diseases, including active peptic ulcer, uncontrolled and recurrent diarrhea, gastrointestinal bleeding, and digestive system neoplastic diseases.
Trial design
Treatments tested in this trial
- lactobacillus LS