This study will evaluate the efficacy and safety of 608 in patients with AS.
Able to understand and comply with the protocol requirements, participate and sign the informed consent form (ICF) voluntarily;
At least 18 years of age at the time of signing the ICF, with no gender restrictions;
Meet the 1984 modified New York criteria for ankylosing spondylitis (AS);
Have inadequate response to non-steroidal anti-inflammatory drugs (NSAIDs) or have contraindications/intolerance to NSAIDs treatment;
Patients with other uncontrolled active inflammatory diseases.
Clinical laboratory tests and other tests that reveal abnormalities with clinical significance
Patients who have active Hepatitis B, Hepatitis C or HIV infections as determined by positive results at Screening.
History of cancer.