A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age12-17
SponsorBristol-Myers Squibb

About this trial

The purpose of this study is to evaluate the efficacy, safety, and drug levels of Deucravacitinib (BMS-986165) in adolescent participants with moderate to severe plaque psoriasis

Eligibility criteria

Qualifiers

Participants must have stable plaque psoriasis for 6 months or more prior to Screening.

Participants must have moderate to severe psoriasis defined by:.

Disqualifiers

Participants must not weigh < 30.0 kg at Screening and Day 1.

Participants must not have non-plaque psoriasis (ie, guttate, inverse, pustular, erythrodermic, or drug-induced psoriasis) or any skin condition other than plaque psoriasis that could interfere with assessments of treatment effect at Screening or Day 1.

Participants must not have a history of serious bacterial, fungal, or viral infection requiring hospitalization and intravenous (IV) antimicrobial treatment within 60 days prior to Day 1.

Participants must not have any untreated bacterial infection within 60 days prior to Day 1.

Trial design

Treatments tested in this trial

  • Deucravacitinib
  • Placebo

Treatment groups

366 Participants
are divided into 2 treatment groups

Sponsors and collaborators