A Study to Evaluate the Safety and Efficacy of SCTB35 in Combination With Lenalidomide in Patients With Relapsed or Refractory Follicular Lymphoma

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-80
SponsorSinocelltech Ltd.

About this trial

The purpose of this study is to evaluate the efficacy and safety of SCTB35 in Combination With Lenalidomide in Patients With Relapsed or Refractory Follicular lymphoma (FL).

Eligibility criteria

Qualifiers

Age 18-80 years old

Histologically confirmed Follicular lymphoma (FL) grade 1, 2, or 3a according to WHO 2022 criteria

Relapsed or refractory (R/R) disease to at least one prior systemic regimen that contained an anti-CD20 monoclonal antibody (mAb) in combination with chemotherapy

Judged by the investigator, the participant must urgently need to receive systemic treatment, based on meeting at least one GELF criterion

Disqualifiers

Documented refractoriness to lenalidomide.

Have lenalidomide exposure within 12 months prior to randomization

Trial design

Treatments tested in this trial

  • SCTB35 injection
  • Rituximab
  • Lenalidomide

Treatment groups

93 Participants
are divided into 2 treatment groups

Sponsors and collaborators