Adding Dexmedetomidine Versus Ketamine to Bupivacaine in Fluoroscopy Guided Caudal Analgesia for Lumbosacral Surgeries

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age21-60
SponsorAin Shams University

About this trial

This study will evaluate the effect of adding dexmedetomidine to bupivacaine compared to ketamine in the caudal block on perioperative analgesia in patients undergoing lumbosacral surgeries under general anesthesia.

Eligibility criteria

Qualifiers

Age 21-60 years.

Sex: Both sexes.

American Society of Anesthesiologists (ASA) Physical Status Class-I and II.

Scheduled for lumbosacral surgery under General Anesthesia.

Disqualifiers

Declining to give written informed consent or patients with significant cognitive dysfunction that hinders informed consent.

History of allergy to the medications used in the study.

Contraindications to regional anesthesia (including coagulopathy and local infection).

History of recent analgesic intake or abuse.

Trial design

Treatments tested in this trial

  • Group C (plain bupivacaine (0.125%))
  • Group D (plain bupivacaine (0.125%) + 2μg/kg dexmedetomidine)
  • Group K (plain bupivacaine (0.125%) + 1mg/kg ketamine)

Treatment groups

72 Participants
are divided into 3 treatment groups

Sponsors and collaborators