Botulinumtoxin A as a Treatment for Myalgia and Myofacial Pain in Patient With Temporomandibulardisorders

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age18-50
SponsorRegion Stockholm

About this trial

Both patients and remitters ask for treatment with Botulinumtoxin A (BTX) with the hope that it will be an effective aid for pain, but little is known regarding if the effect is dose dependent.

The aim of this project is to investigate if injections with BTX in the masseter- and temporal muscle is an efficient treatment in patient with myogenous temporomandibular disorders (TMD) and if the effect of BTX is dose dependent.

Eligibility criteria

Qualifiers

Has given a written consent

Diagnose of myalgia, myofacial pain or myofascial pain with referred pain according

Average pain due to NRS ≥ 3 for more than three months

Palpationpain in masseter or temporalis.

Disqualifiers

Treatment with BTX during the last 12 months

Treatment for orofacial pain within the last 3 months.

Systemic inflammatory diseases (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis)

Widespread pain e.g., fibromyalgia

Trial design

Treatments tested in this trial

  • 5U/0,1 ml Botulinum toxin A
  • 10U/0,1 ml Botulinum toxin A

Treatment groups

90 Participants
are divided into 2 treatment groups

Sponsors and collaborators