About this trial
To evaluate the clinical efficacy of albumin paclitaxel combined with carelizumab and FLOT in the neoadjuvant treatment of locally advanced gastric cancer with different immune types
Eligibility criteria
Qualifiers
blood routine examination standards should be met(no blood transfusion within 14 days)
HB≥100g/L,
WBC≥3×109/L
ANC≥1.5×109/L,
Disqualifiers
Previous history of chemotherapy, radiotherapy, targeted drug therapy or immunotherapy
Patients with contraindications for surgical treatment and chemotherapy or whose physical condition and organ function do not allow for major abdominal surgery;
Patients with metastasis;
Having any active autoimmune diseases or a history of autoimmune diseases (such as interstitial pneumonia, uveitis, enteritis, hepatitis, pituitary inflammation, vasculitis, myocarditis, nephritis, hyperthyroidism, hypothyroidism, including but not limited to these diseases or syndromes); Patients with vitiligo or cured childhood asthma/allergies who did not need any intervention in adulthood were excluded; Autoimmune hypothyroidism treated with a stable dose of thyroid replacement hormone; Type 1 diabetes with stable doses of insulin;
Trial design
Treatments tested in this trial
- Camrelizumab
- Albumin Taxol
- FLOT scheme