Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age21-80
SponsorOman Ministry of Health

About this trial

This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site.

Later, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded.

Preoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores.

The results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.

Eligibility criteria

Qualifiers

Males & females

Age range (21-80)

ASA I & II according to (American Society of Anesthesiologists) classification

Single tooth implant

Disqualifiers

Any known allergy to any medications which will be used in the study

Smokers/ Alcoholics

Pregnant and lactating women

Bone augmentation/ sinus lifting required during the surgery

Trial design

Treatments tested in this trial

  • Dexamethasone 4 Mg/mL Injectable Solution
  • Dexamethasone 8Mg Solution for Injection
  • Saline (NaCl 0,9 %) (placebo)

Treatment groups

138 Participants
are divided into 3 treatment groups

Sponsors and collaborators