Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies
Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-70
SponsorColgate Palmolive
About this trial
The purpose of this clinical study is to evaluate and compare how well three different types of toothpaste technologies work to relieve tooth sensitivity, also known as dentin hypersensitivity. The study asks the question: How effective are toothpastes containing 8% Arginine, 8% Arginine with Zinc Phosphate, or 5% Calcium Sodium Phosphosilicate (CSPS) at providing immediate and short-term relief for people suffering from sensitive teeth?
Eligibility criteria
Qualifiers
Sign an Informed Consent Form;
Male or female 18 to 70 years of age, inclusive;
Be in good general health as determined by the study investigators (absence of any condition that, in the opinion of the Principal Investigator, might constitute a risk to the subject while participating in the study. Examples include heart problems, valve/hip replacements, etc);
Willingness to provide information related to their medical history;
Disqualifiers
Gross oral pathology, chronic disease, and/or history of allergies to any of the test products;
Use of a desensitizing oral care product and/or recipient of any dental desensitizing treatment within the past month prior to start of the study;
Advanced periodontal disease and/or treatment for periodontal disease (including surgery) within the past twelve months, dental cleaning it's permitted;
Sensitive teeth with a mobility greater than one;
Trial design
Treatments tested in this trial
- 8% arginine + Zinc toothpaste
- 5% Calcium Sodium Phosphosilicate toothpaste
- 8% arginine toothpaste
Treatment groups
132 Participants
are divided into 3 treatment groupsLocations
Sponsors and collaborators
Colgate Palmolive
Lead sponsor
Federal University of Rio Grande do Sul
Collaborator
Source ClinicalTrials.gov