About this trial
Background: Vertigo as acute symptom seem to be one of most common presentation in ED, can be treated in ED with multiple medication . Objective: This study aimed to compare the therapeutic efficacy of metoclopramide, promethazine and prochloroperazine in patients presenting with signs and symptoms suggestive of acute peripheral vertigo to the ED . Methods: A 3-arm multi-center, randomized, triple-blind, controlled study comparing three treatments for acute vertigo in three medical centers : AlNahdha hospital Oman , Sohar Hospital Oman and AFH hospital Oman. Oman From February 2022 to August 2024.
Eligibility criteria
Qualifiers
□ Acute peripheral vertigo with nausea or vomiting (vas, visual analog scale >5) during their emergency department episode of care for which the attending physician recommending antiemetic, onset with in 3 days .
Age( 18- 60).
Disqualifiers
• Age >60.
Any organic brain disease (Clear central cause; "malignancy with brain metastasis".)
History of epilepsy
Pregnancy.
Trial design
Treatments tested in this trial
- Metoclopramid ( 10mg), IM promethazine (25mg) , IM prochloroperazine( 12.5mg)