Desflurane vs. Propofol for Cardiac Anesthesia
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorXijing Hospital
About this trial
To investigate whether the inhaled anesthetic desflurane, compared with propofol, exerts cardioprotective effects and reduces the incidence of severe postoperative major cardiac events in patients undergoing coronary artery bypass graft (CABG) surgery.
Eligibility criteria
Qualifiers
Patients scheduled for elective coronary artery bypass grafting (CABG)
Age ≥ 18 years old;
Sign the informed consent form.
Disqualifiers
Emergency or urgent operation
Concomitant valve or aortic surgery
History of myocardial infarction in recent 30 days
Current use of myocardial preconditioning-affecting medications, such as sulfonylurea (glibenclamide), allopurinol, theophylline, nicorandil(last dose < 8 hrs), etc
Trial design
Treatments tested in this trial
- Desflurane group
- Propofol group
Treatment groups
3,560 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov