Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia

ConditionCough
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age21-60
SponsorAl-Azhar University

About this trial

The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.

Eligibility criteria

Qualifiers

Aged 21-60 years.

Both genders.

Body mass index < 30 kg/ m2

American Society of Anesthesiology (ASA) physical status I-II.

Disqualifiers

Known allergy to study drugs.

History of psychiatric illness.

Patients with major organ diseases.

Pre-existing neurological deficits.

Trial design

Treatments tested in this trial

  • Dexmedetomidine
  • Magnesium sulfate
  • Lidocaine
  • normal saline

Treatment groups

300 Participants
are divided into 4 treatment groups

Sponsors and collaborators