Effect of Ketamine on Intraoperative Motor Evoked Potentials
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-100
SponsorUniversity of California, San Francisco
The goal of this clinical trial is to learn about the effect of ketamine on intraoperative motor evoked potentials in adult patients undergoing thoracolumbar spinal fusions. Participants will undergo a standard anesthetic. In addition to the standard anesthetic, the patients will be administered increasing doses of ketamine with motor-evoked potentials being measured at each dose, to assess any impacts.
Adult patients (>18 years of age) undergoing posterior spinal fusions.
Sensitivity or allergy to ketamine.
Schizophrenia or other psychotic conditions
Uncontrolled hypertension with systolic blood pressure greater than 180 mmHg
Myocardial Infarction