This is a multicenter, randomized controlled, phase III clinical trial. The purpose of this study is to evaluate the efficacy of standard nutrition treatment versus conventional nutrition treatment in local advanced nasopharyngeal carcinoma patients.
Newly histologic diagnosis of nasopharyngeal carcinoma(WHO II/III);
All genders，range from 18～65 years old;
Karnofsky performance status(KPS) ≥ 80;
Clinical stage III~IVa(AJCC/UICC 8th);
Have some PEG/PEJ contraindications, such as coagulopathy, recent anticoagulant medications and aspirin, gastric ulcer or history of gastric bleeding, portal hypertension combined with abdominal and esophageal fundal varices, pyloric obstruction due to residual stomach under the costal arch after various major gastrectomy or various reasons;
Distance metastases;
Have or are suffering from other malignant tumors;
Participating in other clinical trials;
Sun Yat-sen University
Lead sponsor
Zhongnan Hospital
Collaborator
The First Affiliated Hospital of Xiamen University
Collaborator
Fudan University
Collaborator
Jiangxi Provincial Cancer Hospital
Collaborator
Xijing Hospital
Collaborator
Xiangya Hospital of Central South University
Collaborator
Fujian Cancer Hospital
Collaborator
Zhejiang Cancer Hospital
Collaborator
Cancer Hospital of Guizhou Province
Collaborator