Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorPharmacosmos A/S

About this trial

The goal of this clinical trial is to compare the efficacy and safety of trilaciclib versus placebo in subjects with limited stage small cell lung cancer. The main question it aims to answer is:

Does trilaciclib have a myeloprotective effect in subject with limited stage small cell lung cancer?

Participants will be randomised to receive either trilaciclib or placebo.

Eligibility criteria

Qualifiers

Confirmed diagnosis of Limited-Stage Small Cell Lung Cancer

Complete recovery from prior anti-tumor surgical procedures

Measurable and evaluable disease through tumor assessment

Willingness to participate and sign informed consent form

Disqualifiers

Extensive Stage Small Cell Lung Cancer

Active cardiovascular disease

Known hypersensitivity to trilaciclib, etoposide, carboplatin, cisplatin or any component in their formulations

Pregnant or nursing women

Trial design

Treatments tested in this trial

  • Trilaciclib
  • Saline (0.9% NaCl)

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators