EFFECTIVENESS OF EARLY INFORMATION AND ENDORSMENT BY GP TO INCREASE COLONOSCOPY FOLLOW-UP AND REDUCE DELAYS IN PEOPLE WITH A POSITIVE COLORECTAL CANCER SCREENING TEST. (SUIVICOLO)

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age50-75
SponsorUniversity Hospital, Caen

About this trial

To be effective, organized colorectal cancer screening requires good adherence to diagnostic colonoscopy in the event of a positive test. In France, the rate of diagnostic colonoscopy following a positive colorectal cancer screening test is less than 85%, and the median delay is close to 90 days. After receiving their positive result from the laboratory, individuals with no known follow-up are contacted only six months later by the Regional Cancer Screening Coordination Centers (CRCDC) responsible for following up with individuals who have tested positive. To optimize follow-up with colonoscopy, earlier contact and information about colonoscopy appear to be necessary. The contribution of the general practitioner identified on the test could be an additional lever.

The SUIVICOLO study aims to evaluate the effectiveness on the rate of colonoscopies performed at 6 months of two strategies for optimizing the follow-up of positive results in comparison with control group C (current procedures of the CRCDC Centre Val de Loire without early letter).

The two strategies evaluated will be:

* Group B1: Sending an early letter signed by the CRCDC accompanied by information leaflet about colonoscopy * Group B2: Sending an early letter co-signed by the CRCDC and the general practitioner (identified or provided by the patient on the test identification form) accompanied by information leaflet about colonoscopy.

These strategies will be compared to the current follow-up strategy in a three arm randomized controlled arm.

Eligibility criteria

Qualifiers

Aged between 50 and 75 at the time of the positive colorectal cancer screening test

Residing in one of the departments of the Centre Val de Loire region

Date on which the positive CRC screening test result was sent to the beneficiary recorded

Colorectal cancer screening test results sent to the beneficiary within 30 days of the test being read

Disqualifiers

Subjects who have notified their refusal to allow their data to be used for research purposes will be excluded from the analyses.

Trial design

Treatments tested in this trial

  • Usual care follow-up by CRCDC
  • Information leaflet about colonoscopy follow-up
  • Endorsement of CRCDC letters from the GP

Treatment groups

2,000 Participants
are divided into 3 treatment groups

Sponsors and collaborators

University Hospital, Caen

Lead sponsor

Centre Regional de Coordination des Depistages des Cancer - Pays de la Loire

Collaborator

INSERM U1086 ANTICIPE - Université Caen Normandie

Collaborator

URPS Centre Val de Loire

Collaborator