Efficacy and Safety of Tamsulosin for Children with Posterior Urethral Valve.
ConditionPosterior Urethral Valve
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexMale
AgeUp to 12
SponsorMansoura University
About this trial
To determine whether there is a role for Tamsulosin, A Selective Alpha-1 Adrenergic Blocker, as therapy in children with Posterior Urethral Valve post valve ablation , and whether there are side effects involved.
Eligibility criteria
Qualifiers
Children with a diagnosis of PUV.
Disqualifiers
Patients with other conditions that can potentially affect lower or upper urinary tract functions (e.g. spinal dysraphism, anorectal malformation and prune belly syndrome)
Patients who were treated with urinary diversion as vesicostomy or cutaneous ureterostomy.
Patients who had primary treatment of PUV ablation at other hospitals.
Contraindications to α blocker treatment.
Trial design
Treatments tested in this trial
- Tamsulosin
- Oxybutynin
- Trimethoprim/sulfamethoxazole (TMP/SMZ)
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov