About this trial
The goal of the study is to compare the efficacy, safety and tolerability of solifenacin plus gabapentin versus solifenacin monotherapy for the treatment of women who are suffering from non-neurogenic ОАВ.
The main questions it aims to answer are:
Does combination of Solifenacin and Gabapentin affect the total score and sub-scores of OABSS in females with non-neurogenic ОАВ ? What medical problems do participants have when taking combination of Solifenacin and gabapentin ?
Eligibility criteria
Qualifiers
Overactive bladder symptom score (OABSS) > 5, urgency subscore ≥3, and urge incontinence score≥ 2.
Disqualifiers
Active urinary tract infection
Neurogenic bladder
History of genitourinary malignancy
Stress urinary incontinence (SUI) as primary diagnosis, or mixed urinary incontinence with predominant SUI
Trial design
Treatments tested in this trial
- solifenacin combined with gabapentin
- solifenacin monotherapy