Efficacy of Gabapentin Combined With Solifenacin for Non-neurogenic Overactive Bladder in Women

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age18+
SponsorMansoura University

About this trial

The goal of the study is to compare the efficacy, safety and tolerability of solifenacin plus gabapentin versus solifenacin monotherapy for the treatment of women who are suffering from non-neurogenic ОАВ.

The main questions it aims to answer are:

Does combination of Solifenacin and Gabapentin affect the total score and sub-scores of OABSS in females with non-neurogenic ОАВ ? What medical problems do participants have when taking combination of Solifenacin and gabapentin ?

Eligibility criteria

Qualifiers

Overactive bladder symptom score (OABSS) > 5, urgency subscore ≥3, and urge incontinence score≥ 2.

Disqualifiers

Active urinary tract infection

Neurogenic bladder

History of genitourinary malignancy

Stress urinary incontinence (SUI) as primary diagnosis, or mixed urinary incontinence with predominant SUI

Trial design

Treatments tested in this trial

  • solifenacin combined with gabapentin
  • solifenacin monotherapy

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators