About this trial
Chloroprocaine is a short-acting local anesthetic that allows rapid recovery and early ambulation but is currently recommended for procedures lasting 40 minutes or less.
Dexamethasone is commonly used during anesthesia for the prevention of postoperative nausea and vomiting and has also been shown to prolong the duration of analgesia and sensory block after regional anesthesia.
Dexamethasone may therefore extend the duration of chloroprocaine spinal anesthesia, potentially allowing its use for longer surgical procedures while maintaining the benefits of rapid postoperative recovery.
This study aims to evaluate whether intravenous dexamethasone can prolong the effects of spinal anesthesia performed with chloroprocaine in adults undergoing knee arthroscopy.
Eligibility criteria
Qualifiers
Undergoing knee arthroscopy lasting ≤ 40 minutes requiring spinal anesthesia (diagnostic arthroscopy or meniscal surgery),
Signed written informed consent form,
Affiliation to a social security system,
Negative pregnancy test on the day of procedure for non-menopausal patients.
Disqualifiers
Contraindications to spinal anesthesia with intrathecal chloroprocaine
History of diabetes,
Pre-existing peripheral neuropathy,
American Society of Anesthesiologists (ASA) physical status IV,
Trial design
Treatments tested in this trial
- Sodium Chloride 0.9%
- Dexamethasone
- Chloroprocaine Injection [Clorotekal]