Efficacy of Statins Among Major Depressive Disorder
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age20-45
SponsorAin Shams University
About this trial
The goal of this clinical trial is to learn if drug Rosuvastatin 10 mg works to treat MDD in adults. It will also learn about the safety of Rosuvastatin 10 mg .The main questions it aims to answer are:
Does Rusovastatin lower the score of The Montgomery Asberg Depression Rating Scale (MADRS) among adult participants with Major Depression Disorder ( MDD )? What medical problems do participants have when taking drug ABC?
Participants will:
Take Rosuvastatin 10 mg every day for 3 months Visit the clinic once every 4 weeks for checkups and tests Report any side effects for Rosuvastatin 10 mg and reassess the severity of depression using The Montgomery Asberg Depression Rating Scale (MADRS)
Eligibility criteria
Qualifiers
aged between 20 and 45 years;
diagnosis of current MDD, verified using the Structured Clinical Interview for DSM-IV Axis I Disorders, patient version (SCID-I/P);
The Montgomery Asberg Depression Rating Scale (MADRS) score of 7 to 34, indicating mild to moderate depression;
the ability to give informed consent and to comply with standard procedures;
Disqualifiers
lifetime or current SCID-I/P diagnosis of a psychotic disorder;
lifetime SCID-I/P diagnosis of bipolar I or II disorder or alcohol dependence;
acute or unstable systemic medical disorder;
inability to comply with the requirements of informed consent or the study protocol;
Trial design
Treatments tested in this trial
- Rosuvastatin 10 mg tablet.
- Sertraline Pill
Treatment groups
145 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov