HS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age18+
SponsorHansoh BioMedical R&D Company

About this trial

This study is a randomized, open-label, controlled, phase III study to evaluate the efficacy and safety of HS-20089 versus investigator's choice of chemotherapy in patients with platinum-resistant recurrent epithelial ovarian cancer.

Eligibility criteria

Qualifiers

Voluntary participation and written informed consent.

18 years and older, female.

Pathologically diagnosed epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer.

Patients must have platinum-resistant disease

Disqualifiers

Prior treated with TOP1 inhibitors or ADCs with TOP1 inhibitors as payload.

Previous or co-existing malignancies.

Uncontrolled pleural effusion, pericardial effusion, or abdominal effusion requiring clinical intervention.

Received systemic anticancer treatments 4 weeks prior to the initiation of the study treatment.

Trial design

Treatments tested in this trial

  • HS-20089
  • Paclitaxel
  • Doxorubicin
  • Topotecan

Treatment groups

468 Participants
are divided into 2 treatment groups

Sponsors and collaborators