Hyaluronic Acid Injection in Idiopathic Carpal Tunnel Syndrome; is it Effective as Local Corticosteroids

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorMinia University Hospital

About this trial

This study compares the effectiveness of two types of local injections-Hyaluronic Acid (HA) and corticosteroids-for treating mild to moderate idiopathic Carpal Tunnel Syndrome (CTS). Sixty adult patients will be assigned to receive one of the two injections under ultrasound guidance. The goal is to see if HA is as effective as the standard corticosteroid treatment in improving symptoms and nerve function over a 3-month follow-up period.

Eligibility criteria

Qualifiers

Numbness or pain in the Median Nerve (MN) distribution.

Nerve conduction studies (NCS) consistent with CTS as per the AANEM guidelines.

An MN cross-sectional area (CSA) at the wrist >12 mm²

Disqualifiers

Patients with severe symptoms (indication for surgery).

Patients who show improvement on medical treatment.

Patients with previous surgical or injectional CTS treatment.

Coexistence of brachial plexopathy, or thoracic outlet syndrome.

Trial design

Treatments tested in this trial

  • Low Molecular Weight Hyaluronic Acid
  • corticosteroid

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators