ICCRT vs. CRT for Locally Advanced Nasopharyngeal Carcinoma
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-65
SponsorFirst Affiliated Hospital, Sun Yat-Sen University
About this trial
This trial is a multi-center phase III clinical trial. The purpose of this trial is to explore whether concurrent chemoradiotherapy is not inferior to induction chemotherapy combined with concurrent chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma.
Eligibility criteria
Qualifiers
Age 18-65 years old;
Pathologically confirmed non-keratinizing nasopharyngeal carcinoma;
Stage T3-4N0-1 (according to the UICC/AJCC 8th);
No distant metastasis;
Disqualifiers
The purpose of treatment is palliative;
Diagnosed with other malignant tumors at the same time;
Malignant tumor history;
Pregnancy or breastfeeding, or expect to become pregnant during the clinical trial period;
Trial design
Treatments tested in this trial
- Induction Chemotherapy
- Concurrent Chemotherapy
- Definitive Radiotherapy
Treatment groups
447 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov