Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
ConditionInfertility, Male
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexMale
Age18+
SponsorUniversity of Miami
About this trial
This is a study of infertility which often occurs in men with spinal cord injury. Most men with spinal cord injury have a normal sperm count but abnormally low sperm motility - which means that the sperm does not swim well. This study will determine if a medicine given by mouth will improve sperm motility in men with spinal cord injuries. The medicine is called probenecid.
Eligibility criteria
Qualifiers
Subject has a traumatic spinal cord injury.
Subject is male and is 18 years or older.
Disqualifiers
Subject has been injured less than 1 year.
The subject is known to be azoospermic.
The subject has an indwelling urethral Foley catheter.
Subject is under the age of 18 years.
Trial design
Treatments tested in this trial
- Probenecid 500 Milligrams (mg)
- probenecid 250 Milligrams (mg)
- Placebo
Treatment groups
90 Participants
are divided into 3 treatment groupsSponsors and collaborators
University of Miami
Lead sponsor
Congressionally Directed Medical Research Programs
Collaborator
Source ClinicalTrials.gov