About this trial
This randomization study is to compare both intrathecal morphine and intravenous methadone, which are both standard of care, for pain management in patients undergoing retroperitoneal lymph node dissections for primary testicular cancer. Investigators plan to compare their analgesic effectiveness at different postoperative time intervals.
Eligibility criteria
Qualifiers
Patients undergoing a virgin (chemotherapy has not been used) or post- chemotherapy retroperitoneal lymph node dissection for primary testicular cancer at IU Health AAHC
ASA Class 1, 2, 3
Age 18 to 80 years; Male
BMI less than 50kg/m2
Disqualifiers
Any contraindication for neuraxial analgesia
Patient on home methadone at any dose
Any physical, mental or medical conditions which, in the opinion of the investigators, may confound quantifying postoperative pain resulting from surgery.
Known true allergy to the study medications (morphine, bupivacaine, acetaminophen, methadone)
Trial design
Treatments tested in this trial
- Inrathecal Morphine
- Intravenous Methadone