Investigating the Efficacy of Combining Virtual Reality-Based Mirror Therapy (VRMT) and Transcranial Direct Current Stimulation (tDCS) to Improve Upper Limb Recovery in Patients with Stroke

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorKing Saud University

About this trial

This study will investigate whether combining virtual reality-based mirror therapy (VRMT) and transcranial direct current stimulation (tDCS) alongside conventional physical therapy (CPT) will significantly improve hand function for patients with stroke compared to using VRMT or tDCS alone.

Eligibility criteria

Qualifiers

At least 18 years old.

Stroke patients with unilateral cerebral infarction or hemorrhage, more than three months following the stroke.

Adequate cognitive ability to follow instructions (The Arabic version of the Mini-Mental State Examination scores > 24).

Modified Ashworth scale score < 3.

Disqualifiers

visual impairment and field defect or hemi-sensory inattention and unilateral neglect.

Wernicke's aphasia, or global aphasia, leads to difficulty following instructions.

Any contraindication to NIBS.

Other neurological conditions or participation in another study.

Trial design

Treatments tested in this trial

  • Transcranial Direct Current Stimulation
  • Virtual reality
  • Transcranial Direct Current Stimulation compined with virtual reality based mirror therapy
  • Conventional physical therapy

Treatment groups

300 Participants
are divided into 4 treatment groups

Sponsors and collaborators

King Saud University

Lead sponsor

King Fahad Medical City

Collaborator

King Saud Medical City

Collaborator