Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorPopulation Health Research Institute
About this trial
The Low dose ColchicinE in pAtients with peripheral Artery DiseasE to address residual vascular Risk (LEADER-PAD) trial will evaluate if anti-inflammatory therapy with colchicine will reduce vascular events in patients with symptomatic peripheral artery disease.
Eligibility criteria
Qualifiers
Age > 18 years
Written or verbal informed consent from the patient
Disqualifiers
Contraindication to colchicine
Long term requirement for colchicine for another clinical indication
Active diarrhoea
eGFR < 30 mL/min/1.73 m2
Trial design
Treatments tested in this trial
- Colchicine 0.5 MG Oral Tablet
- Colchicine-Placebo
Treatment groups
6,150 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov