Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs

ConditionRib Fractures
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAssiut University

About this trial

In our study, we assess the diaphragmatic function, pain quality and anti-inflammatory properties between low dose infusion of dexmedetomidine normal saline in patients with multiple fracture ribs on conservative treatment.

Eligibility criteria

Qualifiers

Adults (age 18-65 years) of American Society of Anaesthesiologists (ASA) physical status I-II

Traumatic multiple fracture ribs 3 ribs or more, who will be subjected to thorough assessments including chest 3D-CT

Undergoing conservative treatment (chest strappings)

Intractable pain with visual analogue scale (VAS) over 6 after traditional therapies

Disqualifiers

Multiple traumas to body parts other than chest with an abbreviated injury scale over 3

Serious head trauma with a Glasgow coma scale lower than 13

Mechanically ventilated patients

Massive hemothorax

Trial design

Treatments tested in this trial

  • Dexmedetomidine
  • 0.9% saline

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators