Metformin Treatment of Patients with Hand Osteoarthritis
ConditionHand Osteoarthritis
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorMarius Henriksen
About this trial
To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.
Eligibility criteria
Qualifiers
Age ≥18 years
Hand OA according to the ACR criteria
Average finger (2 to 5) pain ≥4 on a 0-10 numeric rating scale (NRS where 10 is worst pain) over the past 30 days
Metformin naive
Disqualifiers
History of, or current signs of medical disease that may affect joints, e.g. rheumatoid arthritis, gout, psoriatic arthritis
Psoriasis
Known malignancy (except successfully treated squamous or basal cell skin carcinoma)
Drug or alcohol abuse in the last year
Trial design
Treatments tested in this trial
- Metformin
- Placebo
Treatment groups
150 Participants
are divided into 2 treatment groupsSponsors and collaborators
Marius Henriksen
Lead sponsor
Frederiksberg University Hospital
Sponsor institution
Source ClinicalTrials.gov