Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age60+
SponsorWashington University School of Medicine
About this trial
The investigation will establish biological plausibility and infrastructure required for a multisite clinical trial evaluating the re-purposing of fluvoxamine to mitigate postoperative delirium risk in geriatric patients undergoing non-cardiac non-intracranial surgery.
Eligibility criteria
Qualifiers
English-speaking
elective non-cardiac or non-intracranial surgery requiring at least a 2-day hospital length of stay
Disqualifiers
Received investigational drug within the last 7 weeks
lack of capacity to provide informed consent
prior known intolerance or allergy to SSRIs or fluvoxamine
planned postoperative ventilation
Trial design
Treatments tested in this trial
- Fluvoxamine
- Placebo
Treatment groups
46 Participants
are divided into 2 treatment groupsSponsors and collaborators
Washington University School of Medicine
Lead sponsor
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov