Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age0-72
SponsorUniversity of Calgary

About this trial

The goal of this clinical trial is to evaluate whether multi-strain probiotics of lactobacillus and bifidobacterium can prevent necrotizing enterocolitis (NEC) in preterm infants born at less than 32 weeks of gestation. The main questions it aims to answer are:

* Does the use of a multi-strain probiotic combination reduce the incidence of NEC in preterm infants? * Are there any adverse effects associated with the administration of this probiotic combination?

Eligibility criteria

Qualifiers

Infants born between <32 0/7 weeks gestation.

Disqualifiers

Major congenital or chromosomal abnormalities

Conditions affecting gastrointestinal systems that prohibit infants from starting on feed in the first 72 hours after birth.

Trial design

Treatments tested in this trial

  • Multi-strain probiotics

Treatment groups

2,170 Participants
are divided into 2 treatment groups

Sponsors and collaborators