The purpose of this study is to compare the efficacy and safety of nab-paclitaxel with solvent-based taxanes as first-line treatment for patients with advanced primary epithelial ovarian cancer (EOC), primary peritoneal carcinoma or fallopian tube carcinoma.
Epithelial ovarian cancer/tubal cancer/peritoneal cancer was diagnosed by histopathology or hydroexfoliation cytopathology of the chest and abdomen, and was classified as stage III-IV according to FIGO（International Federation of Gynecology and Obstetrics）stage
Physical condition Eastern Cooperative Oncology Group PS score: 0-2 points
Participants who had not participated in other drug clinical trials within 4 weeks prior to enrollment
Written informed consent
Patients with low malignant potential ovarian tumors;
Other malignant tumors within the previous 5 years, except for cured cervical carcinoma in situ and non-melanoma skin cancer;
Patients who have previously received chemotherapy or radiotherapy for pelvic cavity;
Patients with central nervous system metastasis or peripheral neuropathy > grade 1;
Women's Hospital School Of Medicine Zhejiang University
Lead sponsor
Jiaxing Maternity and Child Health Care Hospital
Collaborator
Zhejiang University
Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborator
First Affiliated Hospital of Wenzhou Medical University
Collaborator
Second Affiliated Hospital of Wenzhou Medical University
Collaborator
Sun Yat-Sen University Cancer Center
Collaborator
Qilu Hospital of Shandong University
Collaborator
Ningbo No. 1 Hospital
Collaborator
Ningbo Women & Children's Hospital
Collaborator
Sir Run Run Shaw Hospital
Collaborator